Talk:Main Page
[+] About Us
This wiki contains everything a budding mad (gender) scientist needs to further their work! Specifically, the driving goals behind this wiki are to:
- Educate ourselves about the biology underlying transition and developmental sex differentiation.
- Postulate and collect a compendium of hypothetical treatments that warrant further research.
- Reduce harm by bringing together official standards of care for gender identities and intersex conditions.
- Enable access to needed information freely to those who require help navigating the systems.
- Provide a forum for people whom these conditions affect the most to become more educated and involved in the processes of their treatments, advancing healthcare ourselves!
[+] Contact Us
- Come discuss your wild ideas with other mad scientists over on our IRC channels! See the Project community guidelines page for more information.
- CyborGhost, the co-founder and currently active content curator, can usually be reached on our IRC server. Or you can just leave a message on their talk page.
- LilianaUmbra, the research librarian, is often on our IRC server. Or you can post a message on her talk page.
- Mabel, the founder, can be sometimes be found on our IRC server. Or alternatively by leaving a message on her talk page.
[+] All Pages
[+] Recent Changes
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6 June 2025
Research Updates
Testosterone levels achieved by medically treated transgender women in a United States endocrinology clinic.
This study assessed the anonymous medical records of 98 trans women taking spironolactone as part of their feminizing regimen, and assessed how much their testosterone levels dropped over time. * Please note that spironolactone is not an anti-gonadotropin and thus does not aim to suppress testosterone production, instead it is an androgen receptor antagonist and instead prevents androgens from activating the receptor. This is a common misconception that can lead to fairly useless data when testing for testosterone levels.
The Papers page is a thorough compendium of up-to-date trans-specific research with a high quality of evidence, as well as guides on ways to access them, or find more research.
It is at the heart of all our goals stated in the "About Us" tab below, and one of the more polished articles on the wiki having been curated by our research librarian LilianaUmbra.
Portal Index
Below are all the portals to our content categories, where many of our articles are filed away. Many of these subjects have yet to be filled in, so if a link isn't working that is probably the case.